HeartWell Core

Your cholesterol panel is not enough. HeartWell Core shows the particles building plaque in your arteries, the inflammation that makes plaque unstable, and the insulin, liver and kidney changes that drive heart disease years before symptoms. 53 markers, one blood draw, designed and reviewed by a cardiologist.

Designed by a cardiologist · Physician-reviewed results · HSA/FSA cards accepted

Build your panel

Every HeartWell toolkit starts with Core. Add hormones, longevity, or both, all from the same blood draw.

• Core (53 markers): $399
• Core + Hormones (Women 69 / Men 70 markers): $649, adds $250
• Core + Longevity (84 markers): $598, adds $199
• Comprehensive: Core + Hormones + Longevity (Women 100 / Men 101 markers): $848

What Core shows you

• Whether your cholesterol tells the whole story (ApoB, LDL particle number and size)
• Your inherited risk from Lp(a), which every adult should check at least once
• Whether your arteries are inflamed (hs-CRP, Lp-PLA2, homocysteine)
• How well you handle sugar, years before diabetes shows (fasting insulin, glucose, A1c)
• Early liver and kidney strain, including urine albumin
• Your 10- and 30-year heart risk, calculated from your results

Add Hormones

Your hormones and your heart are not separate systems. The Hormones add-on adds a full thyroid panel and sex hormones, so you can see how perimenopause, menopause, low testosterone or a sluggish thyroid are shaping your cholesterol, weight, energy and heart risk.

• Why your cholesterol changed: falling estrogen and a slowing thyroid both raise LDL and ApoB
• Whether your thyroid converts hormone properly (free T3, free T4, reverse T3) and whether autoimmunity is starting (TPO and thyroglobulin antibodies)
• Where your hormones really stand, read together rather than one at a time
• A heart-aware baseline if you are on or considering hormone therapy
• For men: PSA alongside testosterone

Women's panel adds progesterone. Men's panel adds bioavailable testosterone and PSA. If you still have cycles, we will tell you which day to draw.

Add Longevity

Your birthday says one age. Your blood says another. The Longevity add-on adds the blood, kidney, immune and growth-hormone markers we use to calculate your biological age and show which systems are aging fastest. Retest in 6 to 12 months to see whether your plan is moving the number.

• Your biological age, calculated from nine routine blood markers with a published formula (PhenoAge)
• Your true kidney function, measured by cystatin C, which is not skewed by muscle mass
• Hidden immune and inflammatory stress from your full blood count
• Whether a fatty liver is progressing toward scarring (FIB-4 and NAFLD Fibrosis Score)
• Iron status: too little or too much
• Oxidized LDL, IGF-1 and ADMA, which reflect plaque-driving LDL damage, growth-hormone signaling and how well your arteries can relax

Biological age is a research-derived estimate for tracking change over time. It is not a diagnosis.

Comprehensive

Your full picture in one draw: advanced heart and metabolic risk, a full thyroid and sex-hormone panel, and your calculated biological age, reviewed together by a cardiologist so nothing is read in isolation. Best for annual deep-dive testing, executive health, and anyone managing hormonal change and long-term aging goals at the same time.

Included: Quest lab draw and urine sample · your physician-reviewed HeartWell report with calculated risk scores (and biological age with Longevity) · optional: a virtual Step 1 Explore visit to go over your results with Dr. Druz, booked separately at holisticheartcenters.com

How it works

1. Order your toolkit. We send your lab order and instructions by email.
2. Visit any Quest patient service center for one blood draw and a urine sample. Fast for 8 to 12 hours; water is fine.
3. You receive your physician-reviewed HeartWell report: every marker, plus the risk scores and ratios we calculate from them.
4. Optional: book a virtual Step 1 Explore visit to go over your results with Dr. Druz and leave with a personalized plan.

Availability: Available in all states except New York, New Jersey and Rhode Island. If you live in one of those states, schedule a free 30-minute call with our patient coordinator to discuss your options. Schedule a free call

Frequently asked questions

Do I need a doctor's order?

No. A licensed physician orders every toolkit as part of your purchase, and every HeartWell report is physician-reviewed.

Do I need to fast?

Yes, 8 to 12 hours before your draw. Water and usual medications are fine unless your doctor told you otherwise.

Does insurance cover it? Can I use my HSA or FSA?

HeartWell is cash-pay and is not billed to insurance. We accept HSA/FSA cards, and toolkits may be HSA/FSA eligible; please check with your HSA or FSA plan to confirm eligibility.

Which panel should I choose?

Most people start with Core. Add Hormones for menopause, low testosterone or thyroid symptoms; add Longevity to know your biological age. Choose Comprehensive to get both add-ons from the same draw.

Do I have to see a doctor to get my results?

No. Every toolkit includes a physician-reviewed HeartWell report. If you would like to go over it together, book a virtual Step 1 Explore visit with Dr. Druz.

I live in New York, New Jersey or Rhode Island. Can I order?

Not online yet. Schedule a free 30-minute call with our patient coordinator to discuss your options.

Can I add genetics later?

Yes. Genetics is collected at home and can be ordered at any time.

Compare all HeartWell toolkits

All 53 Core markers

• Lipids (8): total cholesterol, LDL cholesterol, HDL cholesterol, triglycerides, non-HDL cholesterol, total cholesterol/HDL ratio, apolipoprotein B, lipoprotein(a)
• Lipoprotein particles (6): LDL particle number, small LDL, medium LDL, large HDL, LDL pattern, LDL peak size
• Inflammation and vascular (3): hs-CRP, Lp-PLA2, homocysteine
• Metabolic (4): glucose, hemoglobin A1c, insulin, uric acid
• Fatty acids (10): EPA, DHA, DPA, EPA+DPA+DHA, arachidonic acid, AA/EPA ratio, linoleic acid, omega-3 total, omega-6 total, omega-6/omega-3 ratio
• Liver and protein (9): ALT, AST, alkaline phosphatase, GGT, albumin, globulin, albumin/globulin ratio, total protein, total bilirubin
• Kidney and electrolytes (10): BUN, creatinine, BUN/creatinine ratio, eGFR, sodium, potassium, chloride, carbon dioxide, calcium, urine albumin/creatinine ratio
• Vitamins and minerals (2): vitamin D (25-OH), RBC magnesium
• Thyroid (1): TSH

What Hormones adds

• Thyroid (both): free T3, free T4, free T4 index (T7), reverse T3, total T3, total T4, TPO antibodies, thyroglobulin antibodies
• Sex hormones (both): estradiol, FSH, LH, DHEA-S, SHBG, free testosterone, total testosterone
• Women only: progesterone
• Men only: bioavailable testosterone, PSA (total)

What Longevity adds (31 markers)

• Blood count (20): white blood cells, red blood cells, hemoglobin, hematocrit, MCV, MCH, MCHC, RDW, platelets, MPV, neutrophils, lymphocytes, monocytes, eosinophils, basophils (each as count and %)
• Iron (4): ferritin, iron, total iron-binding capacity, iron saturation
• Kidney (2): cystatin C, cystatin C eGFR
• Growth hormone axis (2): IGF-1, IGF-1 Z-score
• Vascular (3): oxidized LDL, ADMA, SDMA

HeartWell Toolkits are laboratory tests ordered and reviewed by a licensed physician. Results are for health assessment and do not replace an evaluation by your own doctor. If you have symptoms such as chest pain or shortness of breath, seek care immediately.