Perimenopause and Menopause Supplement Pack

Physician-Curated Perimenopause and Menopause Supplement Pack

The Perimenopause and Menopause Supplement Pack is a four-formula protocol selected by board-certified cardiologist Dr. Regina Druz for women navigating perimenopause and menopause. Rather than chasing a single symptom, it addresses the three systems that shift together as estrogen declines: hormone metabolism, metabolic and cardiovascular health, and bone integrity. Every formula is from Designs for Health, a practitioner-grade brand that third-party tests for purity and potency.

What's in the Pack

• FemGuard + Balance: Supports healthy estrogen metabolism and detoxification with DIM, calcium D-glucarate, and TrueBroc broccoli seed extract (sulforaphane glucosinolate), plus black cohosh and chaste tree for hormonal comfort, trans-resveratrol, green tea polyphenols, and methylated B6, folate, and B12.
• Metabolic Synergy: A comprehensive multivitamin built around glucose and insulin metabolism, with chromium, R-lipoic acid, benfotiamine, taurine, carnosine, and annatto tocotrienols alongside fully chelated minerals and active B vitamins.
• Osteoben: Supports bone mineral density with vitamin D3, calcium and magnesium as di-malates, zinc, vitamins K1 and K2, and genistein from Japanese sophora.
• BRF 45: Delivers 45 mg of vitamin K2 as menaquinone-4 with vitamin K1 and geranylgeraniol to support bone formation and direct calcium into bone rather than arterial walls.

Key Benefits

• Healthy Estrogen Metabolism: DIM, sulforaphane precursors, and calcium D-glucarate support favorable estrogen metabolite ratios and phase II liver clearance.
• Metabolic Support in Midlife: Insulin sensitivity typically declines after menopause; chromium, lipoic acid, and benfotiamine support healthy glucose handling.
• Bone Density Protection: Bone loss accelerates in the first years after menopause; vitamin D3, bioavailable calcium and magnesium, and high-dose MK-4 support bone mineralization.
• Cardiovascular-Minded Formulation: Vitamin K2 activates matrix Gla protein, which helps keep calcium out of the arterial wall, an angle most hormone supplements ignore.

Who Is This For?

This pack is designed for women in perimenopause or menopause who want a structured, physician-curated supplement protocol for hormone balance, metabolic health, and bone strength. It is especially relevant for women with a family history of osteoporosis, rising fasting glucose or weight gain in midlife, or an interest in cardiovascular prevention as estrogen's protective effects wane.

Suggested Use

Follow the directions on each product label. Label serving sizes are 4 capsules of FemGuard + Balance, 6 capsules of Metabolic Synergy, 4 capsules of Osteoben, and 2 softgels of BRF 45 daily, ideally divided between meals. The pack ships as convenient daily packets labeled "Women's Hormone Support," each containing one full day's serving of all four formulas. Review the full protocol with your healthcare provider before starting.

Frequently Asked Questions

What are the best supplements for perimenopause and menopause?

The most useful approach targets the changes that occur together: estrogen metabolism, insulin sensitivity, and bone loss. This pack combines estrogen-metabolism support (DIM, calcium D-glucarate, broccoli seed extract), botanicals traditionally used for menopausal comfort (black cohosh, chaste tree), a metabolic multivitamin, and bone-building nutrients including vitamin D3 and vitamin K2.

Who should not take this pack?

This pack contains high-dose vitamin K and is not appropriate for anyone taking warfarin or other vitamin K antagonists. Women who are pregnant or nursing, have a history of estrogen-sensitive cancer, liver disease, or are taking hormone therapy, thyroid medication, or other prescriptions should consult their physician first, since DIM, genistein, black cohosh, and chaste tree can interact with hormonal pathways and medications.

How is this different from a typical hormone balance supplement?

Most hormone balance supplements for women focus only on botanicals for symptoms. This protocol, curated through an integrative cardiology lens, also addresses the metabolic and vascular changes of menopause, which is when women's cardiovascular risk begins to climb, and pairs bone support with vitamin K2 so calcium is directed to bone rather than arteries.

Can I take this pack with hormone replacement therapy?

Some women use components of this pack alongside HRT, but the combination should be reviewed with your prescribing physician. DIM and genistein influence estrogen metabolism and receptor activity, so dosing decisions belong in a supervised plan.

*These statements have not been evaluated by the Food and Drug Administration. These products are not intended to diagnose, treat, cure, or prevent any disease.